Monday, August 20, 2007

Stem cell cure for diabetes in offing: Gujarat docs


There is good news for diabetes patients as there may be a stem cell cure for the disease.

Dr H L Trivedi and his team from Ahmedabad claim that they have discovered a cell that is present in human fat that can produce insulin, when cultivated.

"If we could transplant stem cells which have the ability to cure diabetes, then it's the final of final and ultimate of ultimate as far as cure for diabetes is concerned,” says Dr Trivedi, who is the director of Institute of Kidney Diseases,

The miracle stem cell can be transplanted into the liver, where it not only multiplies, but produces insulin as well - much like the islet cells that produce insulin in the pancreas.

With the cells present in fat, it would side step the controversy associated with embryonic stem cells. In fact Trivedi feels this could be nature's way of countering insulin.

“There is a strong reason to believe that this is a back-up system generated by nature. Nature has stored these insulin producing cells in our adipose tissue,” says Dr Trivedi.

The discovery couldn't be more relevant today, with India considered the diabetes capital of the world.

However, if Dr Trivedi's team manages to develop this, it would mean treatment for a condition that is the 4th leading cause of death in the world.

So what is the next step?

To begin with, the team will now seek permission from the Internal Review Board of the institute to start using this technique on patients.

Says Dr Trivedi, “Once we get the permissions, we should be able to treat the first 10 patients in a month or so."

The institute has decided to use this technique to treat children with diabetes first.

The treatment will initially cost about one lakh rupees and doctors hope that this will mean the final word in diabetes treatment.

1 comment:

prakashthakrar said...

DEAR FRIENDS,

AFTER EXACT ONE YEAR OF MY MESSAGE TO DIABETICS, I HAVE TO REVIEW MY OWN MESSAGE TO DIABETICS.

THIS ONE YEAR EXPERIENCE OBTAINED WHILE CONSTANT TOUCH WITH PATIENTS TREATED BY THE HONOURABLE TEAM COMPELLED ME TO LET YOU ALL KNOW THE HIGH ALERT AREA WHEN IT COMES TO THE TREATMENT OF HUMAN BEINGS. WHILE POSTING THIS MESSAGE IN THE VAST INTEREST OF DIABETICS, I MUST CLARIFY THAT THESE ARE MY PERSONAL OPINION AND I AM WRITING THIS IN THE CAPACITY OF A FATHER OF A JUVENILE DIABETIC AND NOT AS AN EXPERT :-

A) THEY CREATE STEM CELLS FROM FAT CELLS OF PARENTS OF THE PATIENT THAT ARE TRANSPLANTED TO THE PATIENT. THIS MEANS THAT THE CELLS WILL HAVE IMMUNE SIGNATURE OF PARENTS OF THE PATIENT. THEREFORE THE CELLS ARE TREATED AS FOREIGN CELLS WHICH ARE ATTACKED BY IMMUNE SYSTEM OF THE PATIENT. THIS IMMUNE RESPONSE COULD BE SUPPRESSED OF COURSE BUT IT HAS SOME DANGERS TOO. MAY BE THESE DANGERS ARE GREATER THAN BEING TREATED BY INSULIN TREATMENT VIA INSULIN PUMP OR PEN.

B) THE LONG TERM EFFECTS OF STEM CELL TREATMENT ARE UNKNOWN. IT IS
POSSIBLE THAT THE CELLS RESULTING FROM THE PROCEDURE ARE NOT AS
HEALTHY AS IT SEEMS. THIS IS DUE TO THE MASSIVE CHANGES THAT ARE
NECESSARY TO CREATE STEM CELLS FROM ADULT CELLS. SINCE THESE CELLS
REPRODUCE THEMSELVES THERE IS A POTENTIAL RISK OF CANCER DEVELOPMENT.

I WOULD PROJECT THAT AT LEAST 10 YEARS OF INTENSIVE RESEARCH ARE NECESSARY TO EVALUATE THE SIDE EFFECTS. THIS IS MY PERSONAL OPINION; OF COURSE.

ONE MAY GO THROUGH THE CONTACT DETAILS OF IKDRC PATIENTS WHOSE TRANSPLANTED INSULIN-MAKING STEM CELLS AND ASK ABOUT THE PAST AND RECENT INSULIN DOSES :-

PALAK DINESHBHAI PATEL (15YRS)
IPCL-BARODA
09898008806
09925139206

PRANAV KULINBHAI JOSHI (28YRS)
HARDWARE ENGR, AMDAVAD
07925452260
09898507755

HEMANI YOGENDRA GAUTAM-KOTA-RAJASTHAN (14YRS)

SUNITI-JAYPUR (25YRS)
09351336513

MAYANK PARSRAM SONI-JODHPUR (19YRS)
09414135458


BEST REGARDS,

PRAKASH THAKRAR
INDIA
+91 999 8007 888